Recombinant Human PPT1 protein (N-His)

Catalog No.5085315
Unit Size 10ug / 50ug
Product CategoryRecombinant Protein
Target PPT1
Locus ID 5538
UniProt ID P50897
Expressed Sequence 1-306aa
Expression Host E.coli
Tag 6x His Tag at the N-terminus
Mol. Weight 34 kDa
Purity >85%
Purification NI-NTA affinity purification
Formulation Lyophilized, 0.2um filtered solution of Tris-HCl (pH 8.0)
Reconstitution Reconstitute with distilled PBS
Reactivity Human, Mouse, Rat, Fruit fly
Synonyms palmitoyl-protein thioesterase 1 (PPT1); The protein encoded by this gene is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Defects in this gene are a cause of infantile neuronal ceroid lipofuscinosis 1 (CLN1; or INCL) and neuronal ceroid lipofuscinosis 4 (CLN4) . Two transcript variants encoding different isoforms have been found for this gene.
Storage/Stability -20°C for 2-3 years
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