Ac-[Cys (Acm) 33, 42]-EGF (33-42) amide (Mouse)
This EGF-derived peptide is known as a laminin antagonist. It blocks the stimulatory effects of laminin in cell motility and chick angiogenesis. This peptide binds to a breast cancer- and endothelial cell-associated receptor, which is specific for residues 925 to 933 of the laminin B1 chain. The IC?? values for displacement of laminin are in the range of 1-3 nM, depending on the cells. This peptide has an antimetastatic potential.
| Catalog No. | 5991645 |
| Product Category | Catalog Peptide |
| Sequence | Ac-Cys(Acm)-Val-Ile-Gly-Tyr-Ser-Gly-Asp-Arg-Cys(Acm)-NH2 |
| CAS No. | 122053-92-3 |
| Mol. Formula | C51H82N16O17S2 |
| Mol. Weight | 1255.45 |
| Purity | > 95% |
| MOQ | 1 mg |
| Storage/Stability | -20°C/1 year |
| Shipping | Gel Packs |